ICC/IF
Immunofluorescence analysis of C2C12 cells using CHAT antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.IF-P
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using CHAT antibody with DAB staining.| Product Name | Anti-CHAT antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CHAT |
|---|---|
| Gene Synonyms | CLAT Acetyl CoA choline O acetyltransferase ChAT CHOACTase Choline acetylase choline acetyltransferase Choline O acetyltransferase |
| Gene Full Name | choline O-acetyltransferase |
| Gene Summary | This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010] |
| Molecular Weight(MW) | 83kDa |
| Source | Rabbit |
| Cellular Localization | Cytosol, nucleus, cytoplasm, neuron projection, presynapse |
| SwissProt ID | P28329 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using CHAT antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
IF-P
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using CHAT antibody with DAB staining.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
