IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Claudin18 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using Claudin18 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using Claudin18 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using Claudin18 antibody with DAB staining.WB
Western blot analysis using Claudin18 antibody against Hela(1),Hepg2(2),A431(3) cell .WB
Western blot analysis using Claudin18 antibody against Mouse kidney tissue(1),Mouse brain tissue(2),Mouse liver tissue(3),Mouse lung tissue(4),Mouse heart tissue(5) .| Product Name | Anti-Claudin18 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CLDN18 |
|---|---|
| Gene Synonyms | CLDN18,UNQ778/PRO1572,Claudin-18,CLD18,SFTA5 SFTPJ |
| Gene Full Name | claudin 18 |
| Gene Summary | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010] |
| Molecular Weight(MW) | 28kDa |
| Source | Rabbit |
| Cellular Localization | Cell membrane, tight junction |
| SwissProt ID | P56856 |
|---|
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Claudin18 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using Claudin18 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using Claudin18 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using Claudin18 antibody with DAB staining.
WB
Western blot analysis using Claudin18 antibody against Hela(1),Hepg2(2),A431(3) cell .
WB
Western blot analysis using Claudin18 antibody against Mouse kidney tissue(1),Mouse brain tissue(2),Mouse liver tissue(3),Mouse lung tissue(4),Mouse heart tissue(5) .| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
