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Anti-PKM2 antibody-HRP

Catalog Number:OM660576-HRP
Human;Mouse;Rat
WB;IHC
OM660576-HRP
Discount Price
OM660576-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-PKM2 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol PKM
Gene Synonyms CTHBP
Cytosolic thyroid hormone binding protein
KPYM
OIP 3
Oip3
OIP3
OPA interacting protein 3
p58
PK Muscle type
muscle type
PK2
Pk3
PKM2
PKM
Gene Full Name pyruvate kinase M1/2
Gene Summary This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
Molecular Weight(MW) 58kDa
Source Rabbit
Cellular Localization Cytoplasm, Nucleus
Database Links
SwissProt ID P14618
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using PKM2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using PKM2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PKM2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using PKM2 antibody with DAB staining.

WB

Western blot analysis using PKM2 antibody against Hela(1),Hepg2(2),K562(3),A549(4),A431(5),Huvec(6),Nih3t3(7),Cos-7(8),C2C12(9),Hek293(10),Mcf-7(11),Pc-12(12),Jurkat(13),Raji(14)cell.

WB

Western blot analysis using PKM2 antibody against Mouse skin tissue(1),Rat brain tissue(2),Rat stomach tissue(3).
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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