ICC/IF
Immunofluorescence analysis of C2C12 cells using Ras antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-Ras antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFFC |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NRAS |
|---|---|
| Gene Synonyms | GTPase HRas GTPase KRas GTPase NRas H-Ras-1 H-RASIDX Ha-Ras HAMSV HRAS K RAS2A K RAS2B K RAS4A K RAS4B K-RAS KRAS N-RAS N-terminally processed NRAS p21ras RASH1 RASK2 |
| Gene Full Name | NRAS proto-oncogene, GTPase |
| Gene Summary | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] |
| Molecular Weight(MW) | 21/22kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, Cell membrane, Golgi apparatus |
| SwissProt ID | P01111/P01112/P01116 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using Ras antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
