| Gene Symbol |
PAK2
|
| Gene Synonyms |
PAK2 Serine/threonine-protein kinase PAK 2 Gamma-PAK PAK65 S6/H4 kinase p21-activated kinase 2 PAK-2 p58 |
| Gene Full Name |
p21 (RAC1) activated kinase 2 |
| Gene Summary |
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) |
58kDa |
| Source |
Rabbit |
| Cellular Localization |
Cytoplasm, Membrane, Nucleus |