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Anti-AMPKβ2 antibody-HRP

Catalog Number:OM660837-HRP
Human;Mouse;Rat
WB;IHC
OM660837-HRP
Discount Price
OM660837-HRP-100ul
100ul
Product Profile
Product Name Anti-AMPKβ2 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Recombinant protein
Conjugation HRP
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Mouse
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Purification Affinity purified
Target Information
Gene Symbol PRKAB2
Gene Full Name protein kinase AMP-activated non-catalytic subunit beta 2
Gene Summary The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
Molecular Weight(MW) 30kDa
Cellular Localization nucleoplasm,cytosol,nucleotide-activated protein kinase complex
Database Links
SwissProt ID O43741
Application

WB

Western blot analysis using AMPKβ2 antibody against Rat brain tissue(1),Mouse brain tissue(2) lysate .

IHC

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using AMPKβ2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using AMPKβ2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using AMPKβ2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using AMPKβ2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using AMPKβ2 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.Purified antibody in PBS with 0.05% PC300.
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