| Product Name | Anti-HIF-1β/ARNT antibody-Biotin |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant protein |
| Conjugation | Biotin |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Species Reactivity | HumanMouseRat |
| Purification | Affinity purified |
| Gene Symbol | ARNT |
|---|---|
| Gene Synonyms | ARNT1 bHLHe2 D3Ertd557e Drnt ESTM42 HIF-1-beta HIF-1beta HIF1-beta HIF1B HIF1BETA mKIAA4051 TANGO |
| Gene Full Name | aryl hydrocarbon receptor nuclear translocator |
| Gene Summary | This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] |
| Alternative Names | ARNT Aryl hydrocarbon receptor nuclear translocator 1 basic helix-loop-helix transcription factor class E basic helix-loop-helix protein 2 dioxin receptor nuclear translocator hif 1 HIF-1-beta HIF1 beta HIF1-beta hypoxia inducible factor 1 subunit beta hypoxia-inducible factor 1 beta subunit hypoxia-inducible factor 1-beta |
| Molecular Weight(MW) | 87kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P27540 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
