| Product Name | Anti-P27 Kip1 antibody-AF700 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant protein |
| Conjugation | AF700 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Species Reactivity | HumanMouseRat |
| Purification | Affinity purified |
| Gene Symbol | CDKN1B |
|---|---|
| Gene Synonyms | CDKN4 KIP1 MEN1B MEN4 p27 P27KIP1 |
| Gene Full Name | cyclin dependent kinase inhibitor 1B |
| Gene Summary | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014] |
| Alternative Names | CDKN1B CDN1B cyclin-dependent kinase inhibitor 1B (p27 Kip1) cyclin-dependent kinase inhibitor p27 Cyclin-dependent kinase inhibitor p27 Kip1 P27 CDKN1B p27(KIP1) |
| Molecular Weight(MW) | 27kDa |
| Cellular Localization | Cytoplasm,Endosome,Nucleus. |
| SwissProt ID | P46527 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
