| Gene Symbol |
S100A8/S100A9
|
| Gene Synonyms |
P8 NIF CAGA CFAG CGLA L1Ag MRP8 CP-10 MA387 60B8AG S100-A8 |
| Gene Full Name |
S100 calcium binding protein A8/A9 |
| Gene Summary |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
| Molecular Weight(MW) |
14kDa |
| Cellular Localization |
Cell membrane,Cytoplasm,Cytoskeleton,Membrane,Secreted. |