WB
Western blot analysis using β-Catenin antibody against Mcf-7(1),Hela(2),A549(3),Hek293(4),Jurkat(5),C2C12(6),Pc-12(7),K562(8),A431(9) lysate .IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using β-Catenin antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using β-Catenin antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using β-Catenin antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using β-Catenin antibody with DAB staining.| Product Name | Anti-β-Catenin antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant protein |
| Conjugation | HRP |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Purification | Affinity purified |
| Gene Symbol | CTNNB1 |
|---|---|
| Gene Synonyms | EVR7 CTNNB MRD19 NEDSDV armadillo |
| Gene Full Name | catenin beta 1 |
| Gene Summary | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] |
| Molecular Weight(MW) | 85kDa（observed：100kDa） |
| Cellular Localization | Cell junction,Cell membrane,Cell projection,Cytoplasm, Cytoskeleton,Membrane,Nucleus,Synapse. |
| SwissProt ID | P35222 |
|---|
WB
Western blot analysis using β-Catenin antibody against Mcf-7(1),Hela(2),A549(3),Hek293(4),Jurkat(5),C2C12(6),Pc-12(7),K562(8),A431(9) lysate .
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using β-Catenin antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using β-Catenin antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using β-Catenin antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using β-Catenin antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide.Purified antibody in PBS with 0.05% PC300. |
