WB
Western blot analysis using MEK2 antibody against Huvec(1),Thp-1(2),Nih3t3(3),Mcf-7(4),Hela(5),Hepg2(6),A549(7),Hek293(8),Jurkat(9),C2C12(10),Cos-7(11),Pc-12(12),K562(13),A431(14) lysate .IHC
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using MEK2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using MEK2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using MEK2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using MEK2 antibody with DAB staining.| Product Name | Anti-MEK2 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant protein |
| Conjugation | HRP |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Purification | Affinity purified |
| Gene Symbol | MAP2K2 |
|---|---|
| Gene Synonyms | CFC4 MEK2 MKK2 MAPKK2 PRKMK2 |
| Gene Full Name | mitogen-activated protein kinase kinase 2 |
| Gene Summary | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 45kDa（observed：50kDa） |
| Cellular Localization | Cytoplasm,Membrane. |
| SwissProt ID | P36507 |
|---|
WB
Western blot analysis using MEK2 antibody against Huvec(1),Thp-1(2),Nih3t3(3),Mcf-7(4),Hela(5),Hepg2(6),A549(7),Hek293(8),Jurkat(9),C2C12(10),Cos-7(11),Pc-12(12),K562(13),A431(14) lysate .
IHC
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using MEK2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using MEK2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using MEK2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using MEK2 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide.Purified antibody in PBS with 0.05% PC300. |
