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Anti-α skeletal muscle actin antibody-HRP

Catalog Number:OM660892-HRP
Human;Mouse;Rat
WB;IHC
OM660892-HRP
Discount Price
OM660892-HRP-100ul
100ul
Product Profile
Product Name Anti-α skeletal muscle actin antibody-HRP
Antibody Type Primary Antibodies
Immunogen Recombinant protein
Conjugation HRP
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Mouse
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Purification Affinity purified
Target Information
Gene Symbol ACTA1
Gene Synonyms ACTA
ASMA
CFTD
MPFD
NEM1
NEM2
NEM3
SHPM
CFTD1
CFTDM
CMYO2A
CMYO2B
CMYO2C
CMYP2A
CMYP2B
CMYP2C
Gene Full Name actin alpha 1, skeletal muscle
Gene Summary The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. [provided by RefSeq, Sep 2019]
Molecular Weight(MW) 42kDa
Cellular Localization Cytoplasm, cytoskeleton.
Database Links
SwissProt ID P68133
Application

WB

Western blot analysis using α skeletal muscle actin antibody against Huvec(1),Thp-1(2),Nih3t3(3),Mcf-7(4),Hela(5),Hepg2(6),A549(7),Hek293(8),Jurkat(9),C2C12(10),Cos-7(11),Pc-12(12),K562(13),A431(14) lysate .

IHC

Immunohistochemical analysis of paraffin-embedded cardiac muscle tissues using α skeletal muscle actin antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using α skeletal muscle actin antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.Purified antibody in PBS with 0.05% PC300.
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