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Anti-ERK5 antibody-poly-HRP

Catalog Number:OM660910-poly-HRP
Human;Mouse;Rat
WB;IHC
OM660910-poly-HRP
Discount Price
OM660910-poly-HRP-100ul
100ul
Product Profile
Product Name Anti-ERK5 antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Recombinant protein
Conjugation poly-HRP
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Mouse
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Purification Affinity purified
Target Information
Gene Symbol MAPK7
Gene Synonyms BMK1
ERK4
ERK5
PRKM7
Gene Full Name mitogen-activated protein kinase 7
Gene Summary The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 88kDa(120kDa)
Cellular Localization Cytoplasm, Nucleus.
Database Links
SwissProt ID Q13164
Application

WB

Western blot analysis using ERK5 antibody against Hela(1),A549(2),Hepg2(3),Mcf-7(4),Nih3t3(5),Cos-7(6),Jurkat(7),Hek293(8),P19(9),B16(10),C2C12(11),Raji(12),T24(13) lysate .

IHC

Immunohistochemical analysis of paraffin-embedded Kidney tissues using ERK5 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using ERK5 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using ERK5 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using ERK5 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.Purified antibody in PBS with 0.05% PC300.
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