WB
Western blot analysis using HP-1γ antibody against Hela(1),Nih3t3(2),Cos-7(3),Mouse spleen tissue(4),Rat spleen tissue(5) lysate .IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using HP-1γ antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using HP-1γ antibody with DAB staining.| Product Name | Anti-HP-1γ antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant protein |
| Conjugation | HRP |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Purification | Affinity purified |
| Gene Symbol | CBX3 |
|---|---|
| Gene Synonyms | HECH HP1gamma HP1-GAMMA HP1Hs-gamma |
| Gene Full Name | chromobox 3 |
| Gene Summary | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011] |
| Molecular Weight(MW) | 21kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q13185 |
|---|
WB
Western blot analysis using HP-1γ antibody against Hela(1),Nih3t3(2),Cos-7(3),Mouse spleen tissue(4),Rat spleen tissue(5) lysate .
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using HP-1γ antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using HP-1γ antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide.Purified antibody in PBS with 0.05% PC300. |
