| Gene Symbol |
MAP1LC3A
|
| Gene Synonyms |
LC3
LC3A
ATG8E
MAP1ALC3
MAP1BLC3 |
| Gene Full Name |
microtubule associated protein 1 light chain 3 alpha |
| Gene Summary |
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012] |
| Molecular Weight(MW) |
15(observed:18kDa) |
| Cellular Localization |
Cytoplasmic vesicle, autophagosome membrane ; Lipid-anchor . Endomembrane system ; Lipid-anchor . Cytoplasm,cytoskeleton .LC3-II binds to the autophagic membranes. |
