WB
Western blot analysis using BIN1 antibody against Hek293(1),Pc-12(2),Jurkat(3),Raji(4) cell .WB
Western blot analysis using BIN1 antibody against Mouse brain tissue(1),Rat brain tissue(2) .IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using BIN1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human muscle tissues using BIN1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using BIN1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using BIN1 antibody with DAB staining.| Product Name | Anti-BIN1 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | BIN1 |
|---|---|
| Gene Synonyms | AMPH2 AMPHL SH3P9 |
| Gene Full Name | bridging integrator 1 |
| Gene Summary | This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Mar 2016] |
| Molecular Weight(MW) | 65kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, T-tubule, Endosome, Nucleus |
| SwissProt ID | O00499 |
|---|
WB
Western blot analysis using BIN1 antibody against Hek293(1),Pc-12(2),Jurkat(3),Raji(4) cell .
WB
Western blot analysis using BIN1 antibody against Mouse brain tissue(1),Rat brain tissue(2) .
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using BIN1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human muscle tissues using BIN1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using BIN1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using BIN1 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
