Immunofluorescence analysis of NIH3T3 cells using TrkA+B+C antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
NTRK2 TRKB BDNF/NT-3 growth factors receptor GP145-TrkB Trk-B Neurotrophic tyrosine kinase receptor type 2 TrkB tyrosine kinase Tropomyosin-related kinase B
Gene Full Name
neurotrophic receptor tyrosine kinase 2
Gene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Immunofluorescence analysis of NIH3T3 cells using TrkA+B+C antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.