| Gene Symbol |
NTRK2
|
| Gene Synonyms |
NTRK2 TRKB BDNF/NT-3 growth factors receptor GP145-TrkB Trk-B Neurotrophic tyrosine kinase receptor type 2 TrkB tyrosine kinase Tropomyosin-related kinase B |
| Gene Full Name |
neurotrophic receptor tyrosine kinase 2 |
| Gene Summary |
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| Molecular Weight(MW) |
92kDa(observed:100kDa) |
| Source |
Rabbit |
| Cellular Localization |
Cell membrane, Endosome membrane |