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Anti-Claudin-6 antibody-HRP

Catalog Number:OM661053-HRP
Human;Mouse;Rat
WB;IHC
OM661053-HRP
Discount Price
OM661053-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-Claudin-6 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CLDN6
Gene Synonyms claudin 6
claudin-6
CLD6
Skullin 2
Gene Full Name claudin 6
Gene Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
Alternative Names Claudin6
CLD6
skullin
tight junction molecule claudin 6
transmembrane protein
Molecular Weight(MW) 23kDa
Source Rabbit
Cellular Localization Cell membrane
Database Links
SwissProt ID P56747
Application

WB

Western blot analysis using Claudin-6 antibody against A549(1),Cos-7(2),C2C12(3),Hek293(4) cell .

WB

Western blot analysis using Claudin-6 antibody against Mouse heart tissue(1),Rat heart tissue(2) .

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Claudin-6 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Claudin-6 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300,40% Glycerol.
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