ICC/IF
Immunofluorescence analysis of Hela cells using ACSL4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-ACSL4 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ACSL4 |
|---|---|
| Gene Synonyms | 9430020A05Rik ACS4 FACL4 LACS4 MRX63 MRX68 XLID63 |
| Gene Full Name | acyl-CoA synthetase long chain family member 4 |
| Gene Summary | The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jan 2016] |
| Alternative Names | acyl-CoA synthetase 4 arachidonate--CoA ligase fatty acid-Coenzyme A ligase long chain 4 fatty-acid-Coenzyme A ligase long-chain 4 L MRX63 LACS 4 lignoceroyl-CoA synthase long-chain acyl-CoA synthetase 4 long-chain fatty-acid-Coenzyme A ligase 4 mACS4 |
| Molecular Weight(MW) | 79kDa |
| Source | Rabbit |
| Cellular Localization | Peroxisome membrane, Mitochondrion outer membrane, Microsome membrane, Endoplasmic reticulum membrane, Cell membrane |
| SwissProt ID | O60488 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using ACSL4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
