ICC/IF
Immunofluorescence analysis of Hela cells using MEK7 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-MEK7 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MAP2K7 |
|---|---|
| Gene Synonyms | 5930412N11Rik JNKK JNKK 2 JNKK2 MAPKK 7 MAPKK7 MEK MEK 7 Mek7 MKK7 PRKMK7 SAPKK-4 SAPKK4 sek2 |
| Gene Full Name | mitogen-activated protein kinase kinase 7 |
| Gene Summary | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| Alternative Names | a new family member of MAP kinase kinases c-Jun N-terminal kinase kinase 2 JN JNK kinase 2 JNK-activating kinase 2 JNKK 2 MAP kinase kinase MAP kinase kinase 7 MAP2K4 MAPK/ERK kinase 4 MAPK/ERK kinase 7 MAPKK 4 MAPKK 7 MEK 4 MEK 7 MKK7alpha2 MKK7 MKK7beta1 MKK7 MKK7beta2 MKK7 MKK7gamma1 MKK7 MKK7gamma2 MKK7 protein kinase protein kinase homolog protein kinase mitogen activated kinase 7 SAPK kinase 1 SAPK kinase 4 SAPK/ERK kinase 1 SAPKK-1 SAPKK1 SEK1 stress-activated protein kinase kinase 4 |
| Molecular Weight(MW) | 47kDa |
| Source | Rabbit |
| Cellular Localization | Nucleus, Cytoplasm |
| SwissProt ID | O14733 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using MEK7 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
