| Product Name | Anti-IDH2 antibody-AF350 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF350 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | IDH2 |
|---|---|
| Gene Synonyms | D2HGA2 E430004F23 ICD-M IDH IDH-2 IDHM IDP IDPM mNADP-IDH |
| Gene Full Name | isocitrate dehydrogenase (NADP(+)) 2 |
| Gene Summary | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Alternative Names | ICD-M IDH IDP IDPm isocitrate dehydrogenase (NADP(+)) 2 mitochondrial isocitrate dehydrogenase 2 (NADP+) mitochondrial NADP(+)-specific ICDH NADP+-specific ICDH NADP+-specific isocitrate dehydrogenase oxalosuccinate decarboxylase |
| Molecular Weight(MW) | 51kDa(observed：45kDa |
| Source | Rabbit |
| Cellular Localization | Mitochondrion |
| SwissProt ID | P48735 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
