| Gene Symbol |
LAMTOR1
|
| Gene Synonyms |
2400001E08Rik C11orf59 p18 p27RF-Rho PDRO Ragulator1 |
| Gene Full Name |
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 |
| Gene Summary |
Enables GTPase binding activity and protein-membrane adaptor activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of TORC1 signaling; and regulation of cholesterol transport. Located in lysosome. Part of FNIP-folliculin RagC/D GAP. Is active in Ragulator complex and lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2025] |
| Alternative Names |
FLJ20625 late endosomal/lysosomal adaptor and MAPK and MTOR activator 1 lipid raft adaptor protein p18 p27kip1 releasing factor from RhoA p27Kip1-releasing factor from RhoA p27RF Rho p27RF-Rho protein associated with DRMs and endosomes ragulator complex protein PDRO RhoA activator C11orf59 RhoA activator C11orf59 homolog |
| Molecular Weight(MW) |
18kDa |
| Source |
Rabbit |
| Cellular Localization |
Lysosome membrane,Late endosome membrane |