This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008]
Alternative Names
bovine epithelial chloride channel homolog calcium-activated chloride channel family member 1 calcium-activated chloride channel family member 3 calcium-activated chloride channel protein 1 calcium-dependent chloride channel-1 chloride channel calcium activated 1 chloride channel calcium activated 2 chloride channel calcium activated 3 chloride channel regulator 1 chloride channel calcium activated family member 1 CLCA family member 1 chloride channel regulator gob-5 mCLCA3 protein gob-5 transmembrane glycoprotein