The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011]
Alternative Names
5'-deoxyribose-phosphate lyase 5'-dRP lyase AP lyase DNA pol beta DNA polymerase beta DNA polymerase beta subunit DNA-directed DNA polymerase beta MGC125976 POL B Pol beta POLB polymerase (DNA directed) beta polymerase (DNA) beta polymerase B polymerase beta polymerase-beta