| Product Name | Anti-ABCD1 / ALD antibody-Gold |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | Gold |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ABCD1 |
|---|---|
| Gene Synonyms | ABC42 ALD Aldgh ALDP AMN RGD1562128 |
| Gene Full Name | ATP binding cassette subfamily D member 1 |
| Gene Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008] |
| Alternative Names | adrenoleukodystrophy protein ATP-binding cassette sub-family D (ALD) member 1 ATP-binding cassette subfamily D (ALD) member 1 X-linked adrenoleukodystrophy (ALD) gene homolog |
| Molecular Weight(MW) | 83kDa |
| Source | Rabbit |
| Cellular Localization | Peroxisome membrane, Mitochondrion membrane, Lysosome membrane, Endoplasmic reticulum membrane |
| SwissProt ID | P33897 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
