ICC/IF
Immunofluorescence analysis of HUVEC cells using Metadherin / LYRIC antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-Metadherin / LYRIC antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MTDH |
|---|---|
| Gene Synonyms | 2610103J23Rik 3D3 3D3/Lyric AEG-1 AEG1 D8Bwg1112e LYRIC LYRIC/3D3 |
| Gene Full Name | metadherin |
| Gene Summary | Enables NF-kappaB binding activity; double-stranded RNA binding activity; and transcription coactivator activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of intracellular signal transduction; and regulation of DNA-templated transcription. Located in endoplasmic reticulum; nuclear lumen; and perinuclear region of cytoplasm. Implicated in hepatocellular carcinoma. [provided by Alliance of Genome Resources, Jul 2025] |
| Alternative Names | 3D3/LYRIC astrocyte elevated gene 1 astrocyte elevated gene-1 protein LYRIC LYRIC/ MTDH lysine-rich CEACAM1 co-isolated protein lysine-rich protein metastasis adhesion protein p80 putative CEACAM1 associated protein putative membrane-bound GTPase type II membrane protein |
| Molecular Weight(MW) | 64kDa |
| Source | Rabbit |
| Cellular Localization | Endoplasmic reticulum membrane, Nucleus membrane, Cell junction, tight junction, Nucleus, nucleolus, Cytoplasm, perinuclear region |
| SwissProt ID | Q86UE4 |
|---|
ICC/IF
Immunofluorescence analysis of HUVEC cells using Metadherin / LYRIC antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
