IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using RAP1A + RAP1B antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using RAP1A + RAP1B antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using RAP1A + RAP1B antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using RAP1A + RAP1B antibody with DAB staining.WB
Western blot analysis using RAP1A + RAP1B antibody against K562(1),A431(2),C2C12(3),Hek293(4),Mcf-7(5),Raji(6) cell .WB
Western blot analysis using RAP1A + RAP1B antibody against Mouse kidney tissue(1),Rat brain tissue(2).| Product Name | Anti-RAP1A + RAP1B Receptor I antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | RAP1A/RAP1B |
|---|---|
| Gene Synonyms | RAP1 C21KG G-22K KREV1 KREV-1 SMGP21 K-REV, RAL1B |
| Gene Full Name | RAP1A, member of RAS oncogene family/RAP1B, member of RAS oncogene family |
| Gene Summary | This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]/This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011] |
| Molecular Weight(MW) | 21kDa |
| Source | Rabbit |
| Cellular Localization | Cell membrane, Cytoplasm |
| SwissProt ID | P62834/P61224 |
|---|
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using RAP1A + RAP1B antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using RAP1A + RAP1B antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using RAP1A + RAP1B antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using RAP1A + RAP1B antibody with DAB staining.
WB
Western blot analysis using RAP1A + RAP1B antibody against K562(1),A431(2),C2C12(3),Hek293(4),Mcf-7(5),Raji(6) cell .
WB
Western blot analysis using RAP1A + RAP1B antibody against Mouse kidney tissue(1),Rat brain tissue(2).| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
