The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]
Alternative Names
DHOdehase dihydroorotate dehydrogenase mitochondrial dihydroorotate oxidase human complement of yeast URA1 oxidoreductase flavoprotein DHOdehase