ICC/IF
Immunofluorescence analysis of C2C12 cells usingSuperoxide Dismutase 1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using Superoxide Dismutase 1 antibody with DAB staining.IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using Superoxide Dismutase 1 antibody with DAB staining.| Product Name | Anti-Superoxide Dismutase 1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SOD1 |
|---|---|
| Gene Synonyms | ALS ALS1 B430204E11Rik Cu/Zn-SOD CuZnSOD HEL-S-44 homodimer hSod1 Ipo-1 Ipo1 IPOA SOD Sod-1 sod1 sod1-a sod1-b SOD1L1 SODC STAHP XELAEV_18014289mg xsodb |
| Gene Full Name | superoxide dismutase 1 |
| Gene Summary | The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2020] |
| Alternative Names | amyotrophic lateral sclerosis 1 Amyotrophic lateral sclerosis 1 (ALS1) Cu(2+)-Zn2+ superoxide dismutase Cu Zn superoxide dismutase (EC 1.15.1.1) Cu-Zn superoxide dismutase Cu-Zn superoxide dismutase (EC 1.15.1.1) Cu-Zn superoxide dismutase (EC 1.15.11) Cu-Zn superoxide dismutase C-terminal fragment (150AA) Cu-Zn-superoxide dismutase Cu/Zn SOD Cu/Zn superoxide dismutase CuZn superoxide dismutase epididymis secretory protein Li 44 HGNC:11179 hydrogen sulfide oxidase indophenoloxidase A Indophenoloxidase A (IPOA) indophenoloxidase A soluble cystolic Cu/Zn superoxide dismutase epididymis secretory protein Li 44 SOD soluble SOD1 superoxide dismutase Superoxide Dismutase 1 (SOD1) superoxide dismutase 1 soluble superoxide dismutase 1 soluble superoxide dismutase 1 soluble (amyotrophic lateral sclerosis 1 (adult)) superoxide dismutase 1 soluble S homeolog superoxide dismutase cystolic |
| Molecular Weight(MW) | 16kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, Mitochondrion, Nucleus |
| SwissProt ID | P00441 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells usingSuperoxide Dismutase 1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using Superoxide Dismutase 1 antibody with DAB staining.
IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using Superoxide Dismutase 1 antibody with DAB staining.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
