| Gene Symbol |
EPAS1
|
| Gene Synonyms |
bHLHe73 ECYT4 HIF-2 alpha HIF-2alpha HIF2 alpha HIF2A HLF HRF MOP2 PASD2 |
| Gene Full Name |
endothelial PAS domain protein 1 |
| Gene Summary |
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009] |
| Alternative Names |
basic-helix-loop-helix-PAS protein MOP2 class E basic helix-loop-helix protein 73 EPAS-1 Hif like protein HIF-1-alpha-like factor HIF-1alpha-like factor HIF-2-alpha HIF-related factor HIF1 alpha-like factor HIF1alpha-like factor HIF2-alpha HLF (HIF1alpha-like factor) HRF hypoxia inducible factor 2 alpha subunit hypoxia inducible factor 2a hypoxia inducible transcription factor 2alpha hypoxia-inducible factor 2 alpha hypoxia-inducible factor 2-alpha member of PAS protein 2 mHLF PAS domain-containing protein 2 |
| Molecular Weight(MW) |
96kDa |
| Source |
Rabbit |
| Cellular Localization |
Nucleus, Nucleus speckle |