| Gene Symbol |
MOB1B/MOB1A
|
| Gene Synonyms |
MOB1A C2orf6 MOB4B MOBK1B MOBKL1B MOB1B MOB4A, MOBKL1A |
| Gene Full Name |
MOB kinase activator 1B/MOB kinase activator 1A |
| Gene Summary |
The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]/The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
| Alternative Names |
B1 Mps One Binder kinase activator like 1B (yeast) antibody C2orf6 antibody Chromosome 2 open reading frame 6 antibody FLJ10788 antibody FLJ11595 antibody MATS1 antibody MOB kinase activator 1A antibody MOB1 antibody Mob1 alpha antibody Mob1 homolog 1B antibody |
| Molecular Weight(MW) |
25kDa |
| Source |
Rabbit |
| Cellular Localization |
Cytoplasm, Nucleus |