ICC/IF
Immunofluorescence analysis of Hela cells using RBFOX1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-RBFOX1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | RBFOX1 |
|---|---|
| Gene Synonyms | 2BP1 A2bp A2BP1 FOX-1 FOX1 HRNBP1 |
| Gene Full Name | RNA binding fox-1 homolog 1 |
| Gene Summary | The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
| Alternative Names | A FOX-1 A2BP1 ataxin 2 binding protein 1 ataxin 2-binding protein 1 fox-1 homolog A fox-1-like RNA-binding protein 1 hexaribonucleotide binding protein 1 hexaribonucleotide-binding protein 1 RNA binding protein fox-1 homolog 1 RNA-binding protein |
| Molecular Weight(MW) | 43kDa(observed：53kDa) |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, Nucleus |
| SwissProt ID | Q9NWB1 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using RBFOX1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
