ICC/IF
Immunofluorescence analysis of A549 cells using Actin antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-Actin antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ACTA1 |
|---|---|
| Gene Synonyms | ACTA Acta-2 Acts Actsk-1 ASMA CFTD CFTD1 CFTDM CMYO2A CMYO2B CMYO2C CMYP2A CMYP2B CMYP2C MPFD NEM1 NEM2 NEM3 SHPM |
| Gene Full Name | actin alpha 1, skeletal muscle |
| Gene Summary | The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. [provided by RefSeq, Sep 2019] |
| Alternative Names | a-actin ACTA1 actin actin alpha 1 alpha-actin alpha-actin-1 nemaline myopathy type 3 skeletal muscle alpha-actin |
| Molecular Weight(MW) | 42kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm |
| SwissProt ID | P68133 |
|---|
ICC/IF
Immunofluorescence analysis of A549 cells using Actin antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
