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Anti-ATP6V1A antibody-HRP

Catalog Number:OM661238-HRP
Human;Mouse;Rat
WB;IHC
OM661238-HRP
Discount Price
OM661238-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-ATP6V1A antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol ATP6V1A
Gene Synonyms ARCL2D
ATP6A1
Atp6a2
ATP6V1A1
DEE93
HO68
IECEE3
VA68
Vma1
VPP2
Gene Full Name ATPase H+ transporting V1 subunit A
Gene Summary This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist. [provided by RefSeq, Jul 2008]
Alternative Names 70-kDa subunit
ATPase
H+ transporting
lysosomal (vacuolar proton pump)
alpha 70 kDa
ATPase
H+ transporting
lysosomal 70kD
V1 subunit A
ATPase
H+ transporting
lysosomal 70kDa
V1 subunit A
ATPase
H+ transporting
lysosomal V1 subunit A
ATPase
H+ transporting
lysosomal
subunit A1
ATPase
H+ transporting
V1 subunit A
ATPase
H+ transporting
V1 subunit A1
H(+)-transporting two-sector ATPase
subunit A
H+-transporting ATPase chain A
vacuolar (VA68 type)
lysosomal 70kDa
V-ATPase 69 kDa subunit
V-ATPase 69 kDa subunit 1
V-ATPase A subunit 1
V-ATPase subunit A
V-type proton ATPase (V-ATPase) catalytic subunit A
vacuolar proton pump alpha subunit 1
vacuolar proton pump subunit alpha
vacuolar-type H(+)-ATPase
Molecular Weight(MW) 68kDa
Source Rabbit
Cellular Localization Cytoplasm
Database Links
SwissProt ID P38606
Application

WB

Western blot analysis using ATP6V1A antibody against Hepg2(1),K562(2),A549(3),Huvec(4),Nih3t3(5),C2C12(6),Hek293(7),Mcf-7(8),Pc-12(9) cell.

WB

Western blot analysis using ATP6V1A antibody against Mouse skin tissue(1),Mouse heart tissue(2),Rat lung tissue(3),Rat stomach tissue(4),Rat heart tissue(5) .

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ATP6V1A antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using ATP6V1A antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using ATP6V1A antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using ATP6V1A antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300,40% Glycerol.
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