| Product Name | Anti-ATP6V1A antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ATP6V1A |
|---|---|
| Gene Synonyms | ARCL2D ATP6A1 Atp6a2 ATP6V1A1 DEE93 HO68 IECEE3 VA68 Vma1 VPP2 |
| Gene Full Name | ATPase H+ transporting V1 subunit A |
| Gene Summary | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist. [provided by RefSeq, Jul 2008] |
| Alternative Names | 70-kDa subunit ATPase H+ transporting lysosomal (vacuolar proton pump) alpha 70 kDa ATPase H+ transporting lysosomal 70kD V1 subunit A ATPase H+ transporting lysosomal 70kDa V1 subunit A ATPase H+ transporting lysosomal V1 subunit A ATPase H+ transporting lysosomal subunit A1 ATPase H+ transporting V1 subunit A ATPase H+ transporting V1 subunit A1 H(+)-transporting two-sector ATPase subunit A H+-transporting ATPase chain A vacuolar (VA68 type) lysosomal 70kDa V-ATPase 69 kDa subunit V-ATPase 69 kDa subunit 1 V-ATPase A subunit 1 V-ATPase subunit A V-type proton ATPase (V-ATPase) catalytic subunit A vacuolar proton pump alpha subunit 1 vacuolar proton pump subunit alpha vacuolar-type H(+)-ATPase |
| Molecular Weight(MW) | 68kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm |
| SwissProt ID | P38606 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
