| Product Name | Anti-Glucocorticoid Receptor antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NR3C1 |
|---|---|
| Gene Synonyms | GCCR GCR GCRST GR GRL Grl-1 Grl1 |
| Gene Full Name | nuclear receptor subfamily 3 group C member 1 |
| Gene Summary | This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011] |
| Alternative Names | cytosolic/nuclear receptor glucocorticoid receptor glucocorticoid receptor 1 glucocorticoid receptor alpha glucocorticoid receptor subtype P GR gr alpha GR Kit hGR DL-1 hGR NS-1 nuclear receptor subfamily 3 group C member 1 variant hGR-B(54) nuclear receptor subfamily 3 group C member 1 variant hGR-B(77) nuclear receptor subfamily 3 group C member 1 variant hGR-B(93) nuclear receptor subfamily 3 group C member 1 (glucocorticoid receptor) nuclear receptor polymorphic form OTTHUMP00000222854 OTTHUMP00000222858 putative upstream ORF. Unknown |
| Molecular Weight(MW) | 86kDa(observed：56、86kDa) |
| Source | Rabbit |
| Cellular Localization | Cytoplasm,Nucleus |
| SwissProt ID | P04150 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
