| Product Name | Anti-PRDM16 antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PRDM16 |
|---|---|
| Gene Synonyms | 5730557K01Rik CMD1LL csp1 KMT8F LVNC8 MEL1 PFM13 |
| Gene Full Name | PR/SET domain 16 |
| Gene Summary | The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Alternative Names | line 27 MDS1/EVI1-like gene 1 PR domain 16 PR domain containing 16 PR domain zinc finger protein 16 PR domain-containing protein 16 PRDM16 PFM13 transcription factor MEL1 |
| Molecular Weight(MW) | 140kDa |
| Source | Rabbit |
| Cellular Localization | Nucleus,Cytoplasm |
| SwissProt ID | Q9HAZ2 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
