| Gene Symbol |
ZFP91
|
| Gene Synonyms |
DMS-8 DSM-8 DSM8 FKSG11 PZF ZFP-91 ZNF757 |
| Gene Full Name |
ZFP91 zinc finger protein, atypical E3 ubiquitin ligase |
| Gene Summary |
The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2. [provided by RefSeq, Oct 2010] |
| Alternative Names |
breast cancer-related protein drug resistance-associated sequence in melanoma 8 penta zinc finger protein RING-type E3 ubiquitin transferase ZFP91 zinc finger protein 757 zinc finger protein 91 homolog zinc finger protein homologous to Zfp91 in mouse |
| Molecular Weight(MW) |
63kDa |
| Cellular Localization |
Nucleus |