ICC/IF
Immunofluorescence analysis of C2C12 cells using P2RX7 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-P2RX7 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | P2RX7 |
|---|---|
| Gene Synonyms | P2X(7) P2X7 P2X7R |
| Gene Full Name | purinergic receptor P2X 7 |
| Gene Summary | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010] |
| Alternative Names | ATP agonist non-selective cationic pore-forming protein ATP receptor ATP-gated ion channel splice variant P2X7(k) ligand gated ion channel MGC20089 P2X purinoceptor 7 P2X purinoceptor 7-like p2X receptor 7 P2X7 P2X7 purinoceptor P2X7 receptor P2X7 cervical cancer susceptibility protein P2Z P2Z receptor purinergic receptor P2X ligand gated ion channel 7 purinergic receptor P2X ligand-gated ion channel 7 purinergic receptor P2X7 purnergic receptor P2X 7 |
| Molecular Weight(MW) | 69kDa(observed：60~75kDa) |
| Cellular Localization | Cell membrane |
| SwissProt ID | Q99572 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using P2RX7 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
