Immunofluorescence analysis of C2C12 cells using Peroxiredoxin 2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]
Alternative Names
Calpromotin epididymis secretory sperm binding protein Li 2a HGNC:9353 MGC4104 natural killer cell-enhancing factor B PRDX2 protector protein Prx II-1 thiol-specific antioxidant 1 thiol-specific antioxidant protein thioredoxin peroxidase 1 thioredoxin reductase thioredoxin-dependent peroxide reductase 1 thioredoxin-dependent peroxiredoxin 2 torin Trx dependent peroxide reductase 1 TSA
Immunofluorescence analysis of C2C12 cells using Peroxiredoxin 2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05% PC300,40% Glycerol.