| Gene Symbol |
CELF1
|
| Gene Synonyms |
1600010O03Rik BRUNOL2 CUG-BP CUG-BP1 CUGBP CUGBP1 D2Wsu101e EDEN-BP HNAB50 NAB50 NAPOR |
| Gene Full Name |
CUGBP Elav-like family member 1 |
| Gene Summary |
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Alternative Names |
50 kDa nuclear polyadenylated RNA-binding protein brain protein F41 bruno-like 2 bruno-like protein 2 CELF-1 CUG RNA-binding protein CUG triplet repeat RNA-binding protein 1 CUG-BP- and ETR-3-like factor 1 CUG-BP1 CUGBP Ela deadenylation factor CUG-BP deadenylation factor EDEN-BP EDEN-BP homolog embryo deadenylation element binding protein embryo deadenylation element-binding protein homolog nuclear polyadenylated RNA-binding protein 50-kD RNA-binding protein RNA-binding protein BRUNOL-2 RP23-147D3.7 |
| Molecular Weight(MW) |
52kDa(observed:37kDa) |
| Cellular Localization |
Cytoplasm,Nucleus |