ICC/IF
Immunofluorescence analysis of HUVEC cells using SIRT7 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-SIRT7 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Antigen peptide affinity chromatography |
| Gene Symbol | SIRT7 |
|---|---|
| Gene Synonyms | SIR2L7 |
| Gene Full Name | sirtuin 7 |
| Gene Summary | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008] |
| Alternative Names | MGC126840 MGC126842 NAD-dependent deacetylase sirtuin-7 NAD-dependent protein deacylase sirtuin-7 regulatory protein SIR2 homolog 7 silent mating type information regulation 2 S.cerevisiae homolog 7 SIR2-like protein 7 sir2-related protein type 7 sirtuin type 7 sirtuin7 |
| Molecular Weight(MW) | 45kDa(observed：20、45kDa) |
| Cellular Localization | Nucleus, nucleolus, nucleoplasm, Chromosome, Cytoplasm |
| SwissProt ID | Q9NRC8 |
|---|
ICC/IF
Immunofluorescence analysis of HUVEC cells using SIRT7 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
