| Gene Symbol |
SIRT7
|
| Gene Synonyms |
SIR2L7 |
| Gene Full Name |
sirtuin 7 |
| Gene Summary |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008] |
| Alternative Names |
MGC126840 MGC126842 NAD-dependent deacetylase sirtuin-7 NAD-dependent protein deacylase sirtuin-7 regulatory protein SIR2 homolog 7 silent mating type information regulation 2 S.cerevisiae homolog 7 SIR2-like protein 7 sir2-related protein type 7 sirtuin type 7 sirtuin7 |
| Molecular Weight(MW) |
45kDa(observed:20、45kDa) |
| Cellular Localization |
Nucleus, nucleolus, nucleoplasm, Chromosome, Cytoplasm |