| Gene Symbol |
TFAP2B
|
| Gene Synonyms |
AP-2 Ap-2 (a) AP-2(beta) AP-2alpha AP-2B AP-2beta Ap2 AP2-B AP2-beta AP2alpha AP2TF BOFS E130018K07Rik PDA2 Tcfap2a Tcfap2b TFAP2 |
| Gene Full Name |
transcription factor AP-2 beta |
| Gene Summary |
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq, Jul 2008] |
| Alternative Names |
activating enhancer binding protein 2 beta activating enhancer-binding protein 2 alpha activating enhancer-binding protein 2 beta activating enhancer-binding protein 2-alpha activator protein 2 AP-2 beta AP-2 transcription factor AP2-alpha AP2-beta DNA-binding protein (AP-2) FLJ51761 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| Molecular Weight(MW) |
50kDa |
| Cellular Localization |
Nucleus |