Immunofluorescence analysis of A549 cells using ALDH6A1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Alternative Names
aldehyde dehydrogenase family 6 member A1 aldehyde dehydrogenase family 6 subfamily A1 malonate-semialdehyde dehydrogenase malonate-semialdehyde dehydrogenase (acetylating) methylmalonate semialdehyde dehydrogenase methylmalonate-semialdehyde dehydrogenase [acylating] mitochondrial MGC40271 mitochondrial acylating methylmalonate-semialdehyde dehydrogenase MMSDH testicular tissue protein Li 122
Immunofluorescence analysis of A549 cells using ALDH6A1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05% PC300,40% Glycerol.