Enables GTPase binding activity; phosphatidylinositol 3-kinase inhibitor activity; and protein-membrane adaptor activity. Involved in several processes, including early endosome to late endosome transport; macroautophagy; and phosphatidylinositol 3-kinase/protein kinase B signal transduction. Acts upstream of or within endosome to lysosome transport. Located in autophagosome and phagophore assembly site membrane. Is extrinsic component of omegasome membrane and extrinsic component of phagophore assembly site membrane. Part of phosphatidylinositol 3-kinase complex, class III. Is active in phagophore assembly site. [provided by Alliance of Genome Resources, Apr 2025]
Alternative Names
ATG14 autophagy related 14 homolog Atg14-like protein autophagy-related protein 14-like protein Bakor barkor beclin 1-associated autophagy-related key regulator-like Beclin 1-Interacting protein VATG14 autophagy related 14 homolog