ICC/IF
Immunofluorescence analysis of HUVEC cells using BCL2L10 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-BCL2L10 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | BCL2L10 |
|---|---|
| Gene Synonyms | BCL-B bcl2-L-10 Boo Diva |
| Gene Full Name | BCL2 like 10 |
| Gene Summary | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq, Jul 2008] |
| Alternative Names | anti-apoptotic protein Boo anti-apoptotic protein NrH apoptosis regulator Bcl-B bcl-2 homolog Diva BCL2 family protein Boo-like bcl2-L-10 BCL2-like 10 (apoptosis facilitator) death inducer binding to vBcl-2 and Apaf-1 DIVA |
| Molecular Weight(MW) | 22kDa |
| Cellular Localization | Mitochondrion, Nucleus membrane |
| SwissProt ID | Q9HD36 |
|---|
ICC/IF
Immunofluorescence analysis of HUVEC cells using BCL2L10 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
