Immunofluorescence analysis of HUVEC cells using DDX20 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008]
Alternative Names
component of gems 3 DDX 20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 DEAD box protein 20 DEAD box protein DP 103 dead box protein ROSF DEAD-box protein DP103 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20 103kD DEAD/H BOX 20 DKFZP434H052 DP 103 dp103 gemin-3 regulator of steroidogenic factor 1 ROSF-1 similar to Homo sapiens mRNA cDNA DKFZp43H052 (from clone DKFZp434H052) with GenBank Accession AL133598.1 SMN-interacting protein
Immunofluorescence analysis of HUVEC cells using DDX20 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05% PC300,40% Glycerol.