ICC/IF
Immunofluorescence analysis of C2C12 cells using ADAMTS1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-ADAMTS1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ADAMTS1 |
|---|---|
| Gene Synonyms | ADAM-TS1 ADAMTS ADAMTS-1 C3-C5 METH-1 METH1 |
| Gene Full Name | ADAM metallopeptidase with thrombospondin type 1 motif 1 |
| Gene Summary | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008] |
| Alternative Names | a disintegrin and metalloproteinase a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif 1 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 1 ADAM ADAM-TS 1 ADAM-TS1 ADAMs ADAMTS-1 ADAMTS1 extracellular protein with metalloprotease and TSP domains human metalloproteinase with thrombospondin type 1 motifs metalloendopeptidases metalloprotease and thrombospondin-1 METH-1 |
| Molecular Weight(MW) | 105kDa(observed：130kDa、85kDa) |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| SwissProt ID | Q9UHI8 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using ADAMTS1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
